This icon clearly reflects the influence of the Italian Renaissance on the work of the icon painters of Crete, which from the 13th to late 17th century was ruled by Venice. St. John points to the Christ Child with his right hand, while in his left is a scroll which bears the words in Latin Ecce Agnus Dei (Behold the Lamb of God). The Latin script may indicate that this particular icon was ordered from Crete or that it could have been painted in the Venetian Republic itself. St. Catherine holds the wheel and martyr's palm in her left hand, while her right is extended towards the Child who is about to place a ring on her index finger. The ring represents her chastity and marriage to Christ in the Church.