BERNARD, Claude (1813-78). Introduction a l'étude de la médicine expérimentale, Paris: J. B. Baillière and Sons, 1865. 8° (220 x 140mm). Half title. (A few light spots.) Modern morocco-backed boards, original wrappers bound in. Provenance: Ch. Dufay (signature on front wrapper). FIRST EDITION, ?first impression. "Probably the greatest classic on the principles of physiological investigation and of the scientific method as applied to the life sciences." (PMM). GM 1766.501; PMM 353; Waller 951.